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There's research showing that precursors such as NR and NMN can increase blood NAD+ levels, but that seems different from proving a noticeable real-world benefit. How should consumers distinguish between a supplement successfully changing a biomarker and actually improving health or performance? The site's own research article makes this distinction when discussing NAD+ supplements.
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I know this thread is a bit old, but I wanted to chime in because this question stuck with me. I think the real issue is that blood NAD+ is just a proxy, not proof of effect. Have you looked into measuring things like energy, sleep quality, or even blood panels for inflammation before and after supplementing? What specific outcome would convince you personally that it is working beyond the lab result?